A New Class of Medicine
A New Class of Medicine
NaNots are a powerful new class of medicine that treats disease by depleting specific soluble signal molecules from blood.
Soluble signal molecules carry information between cells, which respond in various ways to these signals. If cells are computers, signal molecules are the inputs and outputs. Signal molecules link the genomes and epigenomes of cells to each other, like a computer network.
NaNots are a powerful new class of medicine that treats disease by depleting specific soluble signal molecules from blood.
Soluble signal molecules carry information between cells, which respond in various ways to these signals. If cells are computers, signal molecules are the inputs and outputs. Signal molecules link the genomes and epigenomes of cells to each other, like a computer network.
Diseases form or persist when the wrong soluble signals pass between cells – or essential signals fail to get through.
For instance, inflammatory cytokines – aka “death signals” – intended for focal delivery to bad cells can cause serious, even fatal conditions like sepsis when elevated systemically.
Diseases form or persist when the wrong soluble signals pass between cells – or essential signals fail to get through.
For instance, inflammatory cytokines – aka “death signals” – intended for focal delivery to bad cells can cause serious, even fatal conditions like sepsis when elevated systemically.
On the other hand, cancer cells secrete soluble immune inhibitors that are normally only used for healthy immune regulation.
Many drugs target cells, even when the associated disease is really a signal disorder.
On the other hand, cancer cells secrete soluble immune inhibitors that are normally only used for healthy immune regulation.
Many drugs target cells, even when the associated disease is really a signal disorder.
Some drugs do target signals, yet induce toxicity by failing to distinguish pathogenic soluble molecules from vital membrane forms of the same target.
NaNots are engineered to deplete soluble targets from blood, without any effect on membrane forms of the same target.
Some drugs do target signals, yet induce toxicity by failing to distinguish pathogenic soluble molecules from vital membrane forms of the same target.
NaNots are engineered to deplete soluble targets from blood, without any effect on membrane forms of the same target.
NaNots are blazingly fast, typically depleting their targets by greater than 90% in less than 5 minutes post-injection. NaNots themselves are cleared naturally by macrophage phagocytosis within hours.
NaNots are blazingly fast, typically depleting their targets by greater than 90% in less than 5 minutes post-injection. NaNots themselves are cleared naturally by macrophage phagocytosis within hours.
We’re developing NaNots against major inflammatory and inhibitory targets driving a broad range of diseases.
NaNots fill a void in the pharmacopoeia and hold the promise of powerful new therapeutics with unparalleled safety.
We’re developing NaNots against major inflammatory and inhibitory targets driving a broad range of diseases.
NaNots fill a void in the pharmacopoeia and hold the promise of powerful new therapeutics with unparalleled safety.
